Alzheimer’s Drug Discovery Foundation: Therapeutics Funding Program Grants

The mission of the Alzheimer’s Drug Discovery Foundation is to rapidly accelerate the discovery of drugs to prevent, treat and cure Alzheimer’s disease. The ADDF provides funding to academic centers and biotechs from around the world that are advancing therapeutic and biomarker development for Alzheimer’s and related dementias. The foundation is currently accepting applications for the following programs:

Drug Development 
Amount: Up to $5,000,000 based on stage and scope of research
This award supports investigational new drug (IND)-enabling studies (or the international equivalent) and early-phase clinical trials that test promising pharmacological interventions and devices for Alzheimer’s disease (AD) and related dementias. Both disease-modifying and symptomatic agents will be considered.

Neuroimaging and CSF Biomarker
Amount: Up to $600,000 for one year
The aim of this RFP is to further develop and validate established biomarkers for which there is a clear clinical need in Alzheimer’s disease and related dementias. This RFP prioritizes biomarkers with a defined context of use, a clear advantage over other relevant biomarkers, and a path to commercialization and/or clinical use.

Amount: Up to $5,000,000 for clinical trials based on stage and scope of research
This award supports studies of cognitive symptoms due to health conditions, comparative effectiveness research, and epidemiological studies that probe whether the use or choice of drugs alters the risk for dementia or cognitive decline.