Cystic Fibrosis Foundation: Research Grant Program

The Cystic Fibrosis Foundation works to cure cystic fibrosis and provide all people with CF the opportunity to lead long, fulfilling lives.

To that end, the foundation invites applications for its research grants program, which will award grants of up to $125,000 per year for up to two years in support of research that provides new information and contributes to the understanding of the basic etiology and pathogenesis of cystic fibrosis.

The program works to support efforts that will improve the understanding of disease pathogenesis, such as defects in airway defense, microbial adaption to the CF lung, mucociliary clearance, and airway hydration, and extrapulmonary manifestations of the disease. Priority will be given to projects that propose a better understanding of the mechanisms behind disease pathophysiology and developing strategies to prevent or treat CF.

Emerging areas of interest to the CF Foundation include direct and indirect influences of CFTR modulation on the airway milieu, including resident pathogens, inflammation and inflammatory cell function, mucin structure (tethered and secreted), airway surface liquid (ASL), and mucociliary clearance; mechanisms of defective MCC and ASL that are relevant for therapeutic applications; biological mechanisms involved in lung allograft dysfunction/rejection and transplant immunology; improved understanding of acquisition, detection, pathogenesis, host-pathogen interactions, and treatment approaches for difficult to treat CF infections (i.e., NTM, MDR pseudomonas, MRSA, aspergillus, Burkholderia, stenotrophomonas); approaches to understanding and treating CF-related GI complications, including liver disease and the impact of nutritional deficiencies; and effects of endocrine system dysfunction in CF, including Cystic Fibrosis Related Diabetes (CFRD) and CF bone disease.

Please contact Lynn Wong if you are interested in applying to this opportunity.