Cystic Fibrosis Foundation: Research Grants

The mission of the Cystic Fibrosis Foundation is to cure cystic fibrosis and provide all people with CF the opportunity to lead long, fulfilling lives.

To help advance this mission, the foundation welcomes applications for its Research Grants program. Through the program, grants of up to $125,000 per year for up to two years will be awarded in support of research with potential to contribute to the understanding of the basic etiology and pathogenesis of CF, as well as projects that provide insight into the development of information that may contribute to the development of new therapies for CF.

Priority will be given to projects that propose to better understand the mechanisms behind disease pathophysiology and develop strategies to prevent or treat CF. Emerging areas of interest to the CF Foundation include direct and indirect influences of CFTR modulation on the airway milieu, including resident pathogens, inflammation and inflammatory cell function, mucin structure (tethered and secreted), airway surface liquid (ASL), and mucociliary clearance; mechanisms of defective MCC and ASL that are relevant for therapeutic applications; biological mechanisms involved in lung allograft dysfunction/rejection and transplant immunology; improved understanding of acquisition, detection, pathogenesis, host-pathogen interactions, and treatment approaches for difficult to treat CF infections (i.e., NTM, MDR pseudomonas, MRSA, aspergillus, burkholderia, stenotrophomonas); approaches to understanding and treating CF-related GI complications, including liver disease and the impact of nutritional deficiencies; and effects of endocrine system dysfunction in CF, including Cystic Fibrosis Related Diabetes (CFRD) and CF bone disease.