Discovery research includes the search for understanding the causes of disease, unraveling pathways involved in disease, identifying novel drug targets, and testing new strategies to treat disease. The goal for discovery research is to form a solid foundation that informs and accelerates all subsequent drug development. Since each rare disease poses unique challenges to therapy development, discovery research may include various types of studies related to the unmet needs of each disorder including the creation of improved disease models, biomarker discovery, and the identification of the genetic causes of disease, among others.
Discovery Research Grants are awarded to independent, established investigators to accelerate progress toward understanding and treating neuromuscular disease and total $100,000 per year for one to three years. In a very limited number of cases, awards will exceed $100,000 per year, but pre-approval is required before letter of intent submission.
Applicants are strongly encouraged to submit hypothesis-driven applications on innovative research with the following elements in mind:
– Applications should directly relate to a disease in MDA’s program
– Applications should focus on accelerating therapy development for the disease(s) in question.