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Cystic Fibrosis Foundation: Clinical Pilot and Feasibility Award

Grant Amount: Up to $160,000
Deadline: March 19, 2021 (Letters of Intent)
Category: Health Sciences; Cystic Fibrosis,
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The Cystic Fibrosis Foundation is inviting Letters of Intent for its Clinical Pilot and Feasibility Award.

Through the program, grants of up to $80,000 (plus 12 percent for indirect costs) a year for up to two years will be awarded in support of efforts to collect enough preliminary data to determine the best strategies and methods for approaching a major question in CF that ultimately will require assessment through larger-scale research and/or a multi-center clinical trial.

Special consideration will be given to projects that pursue new approaches, under-researched topics, or more creative avenues of research to address the problems of cystic fibrosis. Applications for continued funding of the same project, or for long-term support of an investigator, will not be considered.

Applications may address any topic area advancing CF care, treatment, or research; however, applications addressing the following areas are encouraged: respiratory microorganism detection and treatment; gastrointestinal symptoms (including but not limited to gastroesophageal reflux disease (GERD), Distal Intestinal Obstruction Syndrome (DIOS), and pancreatitis); reducing treatment burden; CF-related diabetes; diet and nutrition; mental health; CF-related liver disease; exercise; sinus disease; allergies and asthma in CF; alternative/holistic treatments and therapies; sexual reproductive health; bone/joint health; and pain management.

To be eligible, applicants must be an independent investigator, defined by the foundation as an individual who is out of fellowship training and whose institution allows them to submit applications for research funding as a principle investigator. Citizens of the United States and applicants from outside the United States are welcome to apply.

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Cystic Fibrosis Foundation: Clinical Research Award

Grant Amount: Between $150,000 - $350,000 per year
Deadline: Letter of Intent Due March 19, 2021
Category: Health Sciences; Cystic Fibrosis,
Additional Information
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Clinical Research Awards are offered to provide support for investigator initiated clinical research projects that have the potential to make an important contribution to the CF Foundation’s mission. Research projects may address diagnosis, treatment, management of disease or symptom, or the pathophysiology of CF using clinical (observational/interventional), translational or epidemiologic study approaches. Applicants must demonstrate access to sufficient numbers of CF patients and appropriate controls.

The CF Foundation seeks applications for the Clinical Research Award from all areas of clinical research that will have an impact on the lives of people with CF. However, the following research areas are of particular interest to the CF Foundation as they will address critical needs of people with CF:
• Studies that investigate CF disease complications (lung, GI tract, liver, pancreas, reproduction, mental health, endocrine etc.)
• Strategies to improve care and quality of life of people with CF
• Assessment and validation of biomarkers, clinical trial tools, outcome measures and efficacy endpoints
• Translational or clinical studies in lung transplant research
• Characterization of CF disease manifestations and management in the era of highly effective modulator therapy
• Novel interventions that improve CF patient care and outcomes
• Studies designed to translate laboratory findings of disease pathogenesis/treatment to clinical evaluation
• Studies that identify and characterize racial, ethnic, and/or societal contributors to CF disease expression and management

Funding Amount: Applicants may request funding of up to $150,000 per year, plus an additional twelve (12) percent indirect costs for single-center clinical  studies; and up to $350,000 per year, plus twelve (12) percent indirect costs for multi-center clinical studies.

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